BERTHELIN Clothilde
Assistant Professor
PHARE
CAMPUS I, CAEN
clothilde.berthelin@unicaen.fr
+33 2 31 56 51 14

Research themes

Keywords:
Extracellular Vesicles-Mollusks -Bivalves-Climatic change-acclimatation-Energy-Reproduction-Hypoxia

My research focuses on the physiology of bivalve molluscs with a main model of study, a species of interest from the Norman coast, the oyster Magallana gigas. I am interested in the metabolic processes of bivalves mediated by environmental conditions, in a context of climate change. My current research focuses on the regulation of responses to environmental changes (hypoxia, temperature, trophic conditions) in oysters through extracellular vesicles.

Methodologies employed:
EVs methodologies, optical, confocal, electron microscopies, cell enrichment techniques, flow cytometry, impedance-based cell analysis and primary cell cultures.

Scientific expertise:

  • Isolation and characterization of extracellular vesicles in oyster
  • In-depth knowledge of the anatomy, organs and tissues of bivalve molluscs, studied in qualitative histology and quantitative imaging.
  • Analysis of stem and proliferative cell in the gonad of M. gigas
  • Investigation of gametogenesis in various bivalve species (M. gigas, Corbicula sp., Ruditapes decussatus) using qualitative histology and quantitative histo-imaging

Teaching and knowledge diffusion

  • Teaching in biology, food product analysis, fundamentals of agronomy in the aquatic products sector
  • Design and animation of workshops at the science festival
  • General public conferences (science festival, inter-age university)

Admin responsabilities

  • Head of integrated engineering tracks in the Bachelor’s degree programs in Life Sciences and Health Sciences (Life Science and Health Sciences), University of Caen Normandy.
  • Head of the Aquatic Products program within ESIX_AgroA, the Food and Agri-Food Engineering School of the University of Caen Normandy.
  • Head of the second year of the food and agri-food engineering cycle and First-year tutored projects
  • Member of the Laboratory Council of MERSEA
  • Member of the School Council of ESIX Normandie
  • Member of the Agri-food Department Council of ESIX Normandie

Image gallery